Scientist Translational Immunology

The Company

Cue Biopharma, Inc., a clinical-stage biopharmaceutical company, is engineering a novel class of injectable biologics to selectively engage and modulate targeted T cells within the body to transform the treatment of cancer and autoimmune diseases. Cue Biopharma is a high growth company and is listed on NASDAQ (CUE). The company is located in Cambridge, Massachusetts in the heart of the life sciences corridor.

Cue Biopharma is building a world-class team of highly motivated, dedicated scientists to help us advance our research and development programs. The company culture is fast-paced and committed to scientific excellence, innovation, and teamwork.

Candidate Profile

We are looking for a motivated Scientist to join our Translational Immunology / Immuno-Oncology group to provide key mechanistic, pre-clinical and translational support for assets in Cue Biopharma’s pipeline. The Scientist will also support, working closely with other departments, the efforts to investigate novel targets and Immuno-STAT™ (Selective Targeting and Activation of T cells) designs. This is an attractive position for a cellular immunologist with significant growth potential.

Key Responsibilities        

  • Planning, executing and analyzing in vitro/ex vivo studies using primary human immune cells (from healthy donors and patients).
  • Isolation and culture of primary human and animal PBMCs and immune cell subsets.
  • Functional studies with human and animal whole blood using flow cytometry, ELISA or MSD-based readouts.
  • Expansion, selection and long-term maintenance of T cell clones/lines.
  • Immunophenotyping using multicolor flow cytometry staining.
  • Conduct experiments, accurately document and effectively communicate data with project team, colleagues and manager. 
  • Contribute collaboratively to team efforts to achieve experimental and organizational goals.


  • Ph.D. in Immunology or relevant field and productive postdoctoral experience OR M.S. in a relevant field with 5+ years of hands-on industry experience executing and documenting in vitro biology studies.  Experience with working with primary human immune cells and related assays is strongly preferred.
  • Experience with multiple transfection/transduction methodologies to generate transient and stably transfected cell lines and primary cells; multicolor flow cytometry, FACS-based immunophenotyping; cellular immunology in vitro assays is highly desirable.
  • Scientifically rigorous, highly organized, and displays significant attention to detail.
  • Self-motivated and able to work independently.
  • Team- and goal-oriented scientist with excellent oral and written communication skills who enjoys working in a fast-paced, small-company environment.

To apply, please email your resume to In the subject line include your name and the posted job title.

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