Contract Research Associate, Translational Immunology

Cue Biopharma, Inc., a clinical-stage biopharmaceutical company, is engineering a novel class of injectable biologics to selectively engage and modulate targeted T cells within the body to transform the treatment of cancer and autoimmune diseases. Cue Biopharma is a high growth company and is listed on NASDAQ (CUE). The company is located in Cambridge, Massachusetts in the heart of the life sciences corridor.

Cue Biopharma is building a world-class team of highly motivated, dedicated scientists to help us advance our research and development programs. The company culture is fast-paced and committed to scientific excellence, innovation, and teamwork.

Candidate Profile

We are seeking a motivated Contract Research Associate to join the Translational Immunology group. The ideal candidate will be experienced in immunology and assay development, and have a strong scientific background in executing, analyzing and troubleshooting in-vitro immunological assays. By working closely with the Translational Immunology team, the candidate will provide key mechanistic support for Cue Biopharma’s preclinical pipeline programs. This is a temporary contract position that could last up to 6 months with the opportunity for extension or conversion to a full-time position.

Key Responsibilities

  • Work independently, and as part of a collaborative team to support in vitro studies aimed at evaluating Cue Biopharma’s autoimmunity platform.
  • Culture human PBMCs, isolate/culture immune cell subsets, and maintain cell lines.
  • Perform immunophenotyping and functional studies using multicolor flow cytometry, ELISpot and MSD.
  • Organize and maintain inventory of reagents needed for experiments.
  • Conduct experiments, accurately document and effectively communicate data with project team, colleagues and manager.
  • Contribute collaboratively to team efforts to achieve experimental and organizational goals.


  • B.S. or M.S. in Biological Sciences or related discipline with 2+ years of experience in a laboratory setting.
  • Experience with primary human cell culture, and development of immunological assays is strongly preferred.
  • Experience with multicolor flow cytometry, including p/MHC multimers, and ELISpot is a plus.
  • Strong organizational skills with ability to accurately record experimental details and observations and analyze data.
  • Self-motivated, team- and goal-oriented scientist with excellent oral and written communication skills
  • Enjoys working in a fast-paced, small-company environment.

To apply, please email your resume to In the subject line include your name and the posted job title.

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