Contract Associate Scientist – Translational Immunology

The Company

Cue Biopharma, Inc., a clinical-stage biopharmaceutical company, is engineering a novel class of injectable biologics to selectively engage and modulate targeted T cells within the body to transform the treatment of cancer, infectious diseases and autoimmune diseases. Cue Biopharma is a high growth company and is listed on NASDAQ (CUE). The company is located in Cambridge, Massachusetts in the heart of the life sciences corridor.

Cue Biopharma is building a world-class team of highly motivated, dedicated scientists to help us advance our research and development programs. The company culture is fast-paced and committed to scientific excellence, innovation, and teamwork.

Candidate Profile

We are looking for a motivated Contract Associate Scientist to join our Discovery and Translational Immunology group to contribute to early discovery and pipeline programs of Cue Biopharma’s growing portfolio. Working closely with members of the group, the Contract Associate Scientist will also support, the efforts to investigate novel targets and Immuno-STAT™ (Selective Targeting and Activation of T cells) designs. This is a temporary, 6-month contract position with the opportunity for extension or conversion to a full-time position.

Key Responsibilities         

  • Isolation of human PBMCs from whole blood or leukopaks
  • Isolation of immune cell subsets from PBMCs
  • PBMC Immunophenotyping using multicolor flow cytometry staining
  • Screening donor PBMCs for reactivity against relevant epitopes for Cue’s programs using different methods including ELISPOT and p/MHC tetramer-staining by flow cytometry
  • Conduct experiments, accurately document in the notebook and inventory system daily
  • Effectively communicate data with project team, colleagues, and manager. 
  • Contribute collaboratively to team efforts to achieve experimental and organizational goals.


  • B.S. in a relevant field with 2-4 years of related laboratory experience, or M.S. in a relevant field with 0-2 years of related laboratory experience.
  • Hands-on industry experience executing and documenting in vitro biology studies is preferred. Preference for experience with working with primary human immune cells.
  • Experience with multicolor flow cytometry / FACS-based immunophenotyping and/or ELISPOT; cellular immunology in vitro assays is highly desirable.
  • Scientifically rigorous, highly organized, and displays significant attention to details.
  • Self-motivated and able to work independently.
  • Team and goal-oriented scientist with excellent oral and written communication skills who enjoys working in a fast-paced, small-company environment. 

To apply, please email your resume to In the subject line include your name and the posted job title.

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